Dr. Meng Cui of HHMI Discusses Deep Tissue Microscopy Technique

Posted by Michael Feinberg on Wed, Aug 01, 2012 @ 02:39 PM

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Our customers are constantly making exciting scientific discoveries and we’re proud of the part our deformable mirrors play in their research. Dr. Meng Cui, Lab Head at Howard Hughes Medical Institute, Janelia Farm Research Campus recently presented the Iterative MultiphotonAdvanced in Biological Photnics Adaptive Compensation Technique (IMPACT) that his team has developed for deep tissue microscopy at a webinar on “Advances in Biomedical Photonics”.  In Dr. Cui’s presentation he discussed IMPACT which utilizes iterative feedback and the nonlinearity of two-photon signals to measure and compensate wavefront distortion introduced in tissue.  He gave details on the imaging results on a variety of biological tissue including brain tissue through mouse skull and labeled  T cells inside lymph nodes and compared his team's technique with conventional adaptive optics methods.   For more details on Dr. Cui’s research you can view the entire webinar which was presented by Photonics Media at http://www.photonics.com/Webinar.aspx?WebinarID=21.  Details of the research can be downloaded from the following site: http://www.pnas.org/content/early/2012/05/09/1119590109.full.pdf

Tags: deformable mirror, adaptive optics, biological imaging, deep tissue microscopy, Howard Hughes Medical Institute, Janelia Farm Research Campus